- Original Article
- Interaction of the mec Regulator Genes in Methicillin Resistant Staphylococcus
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Young Choi, In Seok Lim, Tae Sub Shim, Mi Kyung Lee, Ae Ja Park
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Clin Exp Pediatr. 1998;41(9):1224-1233. Published online September 15, 1998
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Purpose : Low-affinity penicillin-binding protein PBP 2a encoded by mecA is closely related to methicillin resistance in staphylococci, and the expression of PBP 2a is controlled by regulator elements encoded by mecR1 and mecI. Deletion or mutation which occurred in mecI is considered to be associated with constitutive production of PBP 2a. We investigated the distribution of mec regulator genes... |
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